Biochemical pathways supporting beta-lactam biosynthesis in the springtail Folsomia candida

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Biochemical pathways supporting beta-lactam biosynthesis in the springtail Folsomia candida

Recently, an active set of beta-lactam biosynthesis genes was reported in the genome of the arthropod springtail Folsomia candida (Collembola). Evidence was provided that these genes were acquired through horizontal gene transfer. However, successful integration of fungal- or bacterial-derived beta-lactam biosynthesis into the metabolism of an animal requires the beta-lactam precursor L-α-amino...

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Chronic exposure to chlorpyrifos reveals two modes of action in the springtail Folsomia candida.

Organophosphates are popular insecticides, but relatively little is known about their chronic effects on ecologically relevant endpoints. In this paper, we examine a life-cycle experiment with the springtail Folsomia candida, exposed via food to chlorpyrifos (CPF). The results for all endpoints (survival, growth and reproduction) were analyzed using the DEBtox model. Growth was unaffected by CP...

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QSAR development and bioavailability determination: the toxicity of chloroanilines to the soil dwelling springtail Folsomia candida.

Quantitative structure-activity relationships (QSARs) are an established tool in environmental risk assessment and a valuable alternative to the exhaustive use of test animals under REACH. In this study a QSAR was developed for the toxicity of a series of six chloroanilines to the soil-dwelling collembolan Folsomia candida in standardized natural LUFA2.2 soil. Toxicity endpoints incorporated in...

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The effect of counterion and percolation on the toxicity of lead for the springtail Folsomia candida in soil.

In standard soil toxicity tests, heavy metals are amended as water-soluble salts. The role of the counterion in metal salt toxicity is scarcely looked into. In this study, we assessed the contribution of nitrate and chloride to the toxicity of lead to Folsomia candida in a natural standard soil. Both lead salts were tested according the standard test protocol as well as after percolation of the...

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Draft Genome Sequence of Bacillus toyonensis VU-DES13, Isolated from Folsomia candida (Collembola: Entomobryidae)

We present here the draft genome of Bacillus toyonensis VU-DES13, which was isolated from the midgut of the soil-living springtail Folsomia candida Previous research revealed the presence of gene clusters for the biosynthesis of various secondary metabolites, including β-lactam antibiotics, in the host's genome. The genome data are discussed in the light of the antimicrobial properties against ...

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ژورنال

عنوان ژورنال: Biology Open

سال: 2016

ISSN: 2046-6390

DOI: 10.1242/bio.019620